Galvez et al.
HIV broadly neutralizing antibody escape dynamics drive the outcome of AAV-vectored immunotherapy in humanized mice.
Citations: 0
Immunity 2026
Publications
Research publications from The Balazs Laboratory covering immunology, viral pathogenesis, and therapeutic development.
Slein et al.
Antibodies targeting HSV glycoprotein B require effector functions to protect neonatal mice.
Citations: 0
Journal of virology 2026
Roederer et al.
SARS-CoV-2 fusion-peptide-directed antibodies are elicited by natural infection and can mediate broad sarbecovirus neutralization.
Citations: 0
Cell reports 2026
Paxitzis et al.
Antibody responses to SARS-CoV-2 vaccine in nursing home residents support a Bi-annual update schedule.
Citations: 0
Vaccine 2026
Kenney et al.
Immune signatures of SARS-CoV-2 infection resolution in human lung tissues.
Citations: 0
PLoS pathogens 2025
Perugino et al.
Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection
Citations: 4
Cell Rep. 2025
Abul et al.
Broad immunogenicity to prior SARS-CoV-2 strains and JN.1 variant elicited by XBB.1.5 vaccination in nursing home residents
Citations: 4
Geroscience 2025
Oyebanji et al.
COVID-19 booster doses reduce sex disparities in antibody responses among nursing home residents
Citations: 2
Aging Clin Exp Res. 2025
Roederer et al.
Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity
Citations: 7
Cell Rep Med. 2024
Galvez et al.
QuickFit: A High-Throughput RT-qPCR-Based Assay to Quantify Viral Growth and Fitness In Vitro
Citations: 1
Viruses. 2024
Gravenstein et al.
Durability of immunity and clinical protection in nursing home residents following bivalent SARS-CoV-2 vaccination
Citations: 7
EBioMedicine. 2024
Nitido et al.
mRNA-based monkeypox virus vaccine prevents disease in non-human primates
Citations: 3
Cell. 2024
Hauser et al.
Heterologous Sarbecovirus Receptor Binding Domains as Scaffolds for SARS-CoV-2 Receptor Binding Motif Presentation
Citations: 0
ACS Infect Dis. 2024
Wamhoff et al.
Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
Citations: 37
Nat Commun. 2024
Oyebanji et al.
Neutralization and binding antibody response to second bivalent COVID-19 vaccination in nursing home residents
Citations: 4
J Am Geriatr Soc. 2023
Dudley et al.
Rheumatoid arthritis and older age are associated with lower humoral and cellular immune response to primary series COVID-19 mRNA vaccine
Citations: 3
Vaccine. 2023
Joshi et al.
Delivery platforms for broadly neutralizing antibodies
Citations: 5
Curr Opin HIV AIDS. 2023
Meador et al.
Brief Report: Declining Rates of SARS-CoV-2 Vaccine Uptake Among Patients With Thoracic Malignancies
Citations: 2
Clin Lung Cancer. 2023
Luthuli et al.
Generation and characterization of infectious molecular clones of transmitted/founder HIV-1 subtype C viruses
Citations: 2
Virology. 2023
Nugent et al.
Second monovalent SARS-CoV-2 mRNA booster restores Omicron-specific neutralizing activity in both nursing home residents and health care workers
Citations: 9
Vaccine. 2023
Yue et al.
Diagnostic TR-FRET assays for detection of antibodies in patient samples
Citations: 1
Cell Rep Methods. 2023
Freeman et al.
Association of Cytomegalovirus Serostatus With Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Responsiveness in Nursing Home Residents and Healthcare Workers
Citations: 8
Open Forum Infect Dis. 2023
Canaday et al.
SARS-CoV-2 Antibody Responses to the Ancestral SARS-CoV-2 Strain and Omicron BA.1 and BA.4/BA.5 Variants in Nursing Home Residents After Receipt of Bivalent COVID-19 Vaccine - Ohio and Rhode Island, September-November 2022
Citations: 13
MMWR Morb Mortal Wkly Rep. 2023
Atyeo et al.
COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women
Citations: 18
Am J Obstet Gynecol. 2023
Hauser et al.
Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design
Citations: 7
Cell Rep Med. 2022
Backes et al.
Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity
Citations: 16
J Exp Med. 2022
Burns et al.
BNT162b2 induces robust cross-variant SARS-CoV-2 immunity in children
Citations: 9
Vaccines. 2022
Bartsch et al.
SARS-CoV-2 mRNA vaccination elicits robust antibody responses in children
Citations: 30
Sci trans Med. 2022
Canaday et al.
Significant Reduction in Vaccine-Induced Antibody Levels and Neutralization Activity Among Healthcare Workers and Nursing Home Residents 6 Months Following Coronavirus Disease 2019 BNT162b2 mRNA Vaccination
Citations: 29
Clin Infect Dis. 2022
Hauser et al.
Humoral responses to the SARS-CoV-2 spike and receptor binding domain in the context of pre-existing immunity confer broad sarbecovirus neutralization
Citations: 1
Front Immunol. 2022
Brady et al.
Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized miceein A
Citations: 14
Sci Transl Med. 2022
Atyeo et al.
Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms
Citations: 59
Nat Comm. 2022
Canaday et al.
COVID-19 vaccine booster dose needed to achieve Omicron-specific neutralisation in nursing home residents
Citations: 34
eBioMed. 2022
Barmettler et al.
Response to Severe Acute Respiratory Syndrome Coronavirus 2 Initial Series and Additional Dose Vaccine in Patients With Predominant Antibody Deficiency
Citations: 14
J Allergy Clin Immunol Pract. 2022
Casazza et al.
Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial
Citations: 52
Nat Med. 2022
Kenney et al.
Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection
Citations: 23
Cell Rep. 2022
Naranbhai et al.
Comparative Immunogenicity and Effectiveness of mRNA-1273, BNT162b2, and Ad26.COV2.S COVID-19 Vaccines
Citations: 100
J Infect Dis. 2021
Burns et al.
Durability and Cross-Reactivity of SARS-CoV-2 mRNA Vaccine in Adolescent Children
Citations: 11
Vaccines. 2022
Hauser et al.
Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting
Citations: 4
Cell Rep. 2022
Naranbhai et al.
T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals
Citations: 158
Cell. 2022
Vanuytsel et al.
Multi-modal profiling of human fetal liver hematopoietic stem cells reveals the molecular signature of engraftment
Citations: 23
Nat Comm. 2022
Calvet-Mirabent et al.
Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice
Citations: 10
Eur J Immunol. 2022
Garcia-Beltran et al.
mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
Citations: 730
Cell. 2022
Naranbhai et al.
Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer
Citations: 31
Cancer Cell. 2022
Naranbhai et al.
Immunogenicity and Reactogenicity of SARS-CoV-2 Vaccines in Patients With Cancer: The CANVAX Cohort Study
Citations: 65
J Clin Oncol. 2022
Bowes et al.
Heterogeneous immunogenicity of SARS-CoV-2 vaccines in cancer patients receiving radiotherapy
Citations: 10
Radiother Oncol. 2021
Feldman et al.
Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses
Citations: 38
Sci Immunol. 2021
Canaday et al.
Reduced BNT162b2 Messenger RNA Vaccine Response in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-Naive Nursing Home Residents
Citations: 66
Clin Infect Dis. 2021
Oyebanji et al.
Does a lack of vaccine side effects correlate with reduced BNT162b2 mRNA vaccine response among healthcare workers and nursing home residents?
Citations: 16
Aging Clin Exp Res. 2021
Phelps et al.
Contribution to HIV Prevention and Treatment by Antibody-Mediated Effector Function and Advances in Broadly Neutralizing Antibody Delivery by Vectored Immunoprophylaxis
Citations: 15
Front Immunol. 2021
Garcia-Beltran et al.
Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection
Citations: 17
Front Immunol. 2021
Cele et al.
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma
Citations: 444
Nature. 2021
Garcia-Beltran et al.
Multiple SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity
Citations: 739
Cell. 2021
Schiff et al.
T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+ T cells
Citations: 22
Sci Rep. 2021
Yousif et al.
The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells
Citations: 27
Immunity. 2021
Kisalu et al.
Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention
Citations: 22
JCI Insight. 2021
Garcia-Beltran et al.
COVID-19-neutralizing antibodies predict disease severity and survival
Citations: 477
Cell. 2021
Chen et al.
Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production
Citations: 137
Cell. 2020
Crawford et al.
Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays
Citations: 555
Viruses 2020
Keating et al.
Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine Antigens
Citations: 5
J Proteome Res. 2020
Huang et al.
Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids
Citations: 149
PLoS One. 2019
van den Berg et al.
AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region
Citations: 29
Mol Ther Meth Clin Dev. 2019
Welles et al.
Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge
Citations: 42
PLoS Pathog. 2018
Lin et al.
Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1
Citations: 25
Retrovirology 2018
Brady et al.
Antibody gene transfer with adeno-associated viral vectors as a method for HIV prevention
Citations: 37
Immunol Rev. 2017
Payne et al.
Multilineage transduction of resident lung cells in vivo by AAV2/8 for α1-antitrypsin gene therapy
Citations: 8
Mol Ther Meth Clin Dev. 2016
Thomas et al.
Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57
Citations: 13
Exp Hematol. 2016
Akkina et al.
Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID "Meet the Experts" 2015 Workshop Summary
Citations: 43
AIDS Res Human Retr. 2016
Deal et al.
Engineering humoral immunity as prophylaxis or therapy
Citations: 21
Cur Opin Immunol. 2015
Saunders et al.
Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection
Citations: 85
J Virol. 2015
Deal et al.
Vectored antibody gene delivery for the prevention or treatment of HIV infection
Citations: 20
Cur Opin HIV AIDS. 2014
de Jong et al.
Broadly neutralizing antibodies abrogate established hepatitis C virus infection
Citations: 148
Sci Transl Med. 2014
Deal et al.
Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice
Citations: 45
Proc Natl Acad Sci. USA 2014
Balazs et al.
Vectored immunoprophylaxis protects humanized mice from mucosal HIV transmission
Citations: 160
Nat Med. 2014
Balazs et al.
Broad protection against influenza infection by vectored immunoprophylaxis in mice
Citations: 89
Nat Biotech. 2013
Balazs et al.
Antibody-based protection against HIV infection by vectored immunoprophylaxis
Citations: 347
Nature 2011
Sigal et al.
Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy
Citations: 265
Nature 2011
O'Connell et al.
MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output
Citations: 163
Proc Natl Acad Sci. USA 2010
O'Connell et al.
Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations
Citations: 41
PLoS ONE 2010
Austin et al.
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome
Citations: 59
J Clin Invest. 2008
Balazs et al.
Endothelial Protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow
Citations: 158
Blood 2006
Michurina et al.
Nitric oxide is a regulator of hematopoietic stem cell activity
Citations: 21
Mol Ther 2004
Balooch et al.
Viscoelastic properties of demineralized human dentin measured in water with atomic force microscope (AFM)-based indentation
Citations: 50
J. Biomed. Mater. Res. 1998