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Naive human B cells can neutralize SARS-CoV-2 through recognition of its receptor binding domain

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Engineered receptor binding domain immunogens elicit pan-coronavirus neutralizing antibodies


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Cell 2021

Multiple circulating SARS-CoV-2 variants escape neutralization by vaccine-induced humoral immunity

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Scientific Reports 2021

T cell-tropic HIV efficiently infects alveolar macrophages through contact with infected CD4+T cells.

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Immunity 2020

The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

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JCI Insight 2020

Enhancing durability of CIS43 monoclonal antibody by Fc mutation or AAV delivery for malaria prevention

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Viruses 2020

Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 Spike protein for neutralization assays

Keating et al.
Journal of Proteome Research 2020

Spontaneous Glycan Reattachment Following N-Glycanase Treatment of Influenza and HIV Vaccine Antigens.

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PLoS One 2019

Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids.

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Molecular Therapy Methods Clinical Development 2019

AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region.

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PLoS Pathogens 2018

Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.

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Retrovirology 2018

Adeno-associated virus gene delivery of broadly neutralizing antibodies as prevention and therapy against HIV-1.

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Immunological Reviews 2017

Antibody gene transfer with adeno-associated viral vectors as a method for HIV prevention.

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Molecular Therapy Methods Clinical Development 2016

Multilineage transduction of resident lung cells in vivo by AAV2/8 for alpha1-antitrypsin gene therapy.

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Experimental Hematology 2016

Insulin-like growth factor 2 modulates murine hematopoietic stem cell maintenance through upregulation of p57.

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AIDS Research and Human Retroviruses 2016

Improvements and Limitations of Humanized Mouse Models for HIV Research.

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Journal of Virology 2015

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection.

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Current Opinion in HIV & AIDS 2015

Vectored antibody gene delivery for the prevention or treatment of HIV infection.

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Science Translational Medicine 2014

Broadly neutralizing antibodies abrogate established hepatitis C virus infection.

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PLoS ONE 2010

Lentiviral vector delivery of human interleukin-7 (hIL-7) to human immune system (HIS) mice expands T lymphocyte populations.

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MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output.

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Blood 2006

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Viscoelastic properties of demineralized human dentin measured in water with atomic force microscope (AFM)-based indentation.